Etofenamate EP Impurity B
ufenamate
CAS: 67330-25-0
Molecular Formula: C18H18F3NO2
Etofenamate EP Impurity B - Names and Identifiers
| Name | ufenamate |
| Synonyms | HF-264 Combec ufenamate 67330-25-0 Ufenamate (JAN) BUTYL FLUFENAMATE Butyl fulfenamate Etofenamate EP Impurity B FLUFENAMIC ACID BUTYL ESTER n-Butyl N-(3-trifluoromethylphenyl)anthranilate butyl 2-{[3-(trifluoromethyl)phenyl]amino}benzoate N-(a,a,a-Trifluoro-m-tolyl)anthranilic Acid Butyl Ester 2-[[3-(Trifluoromethyl)phenyl]amino]benzoic acid butyl ester 2-((3-(Trifluoromethyl)phenyl)amino)benzoic Acid Butyl Ester |
| CAS | 67330-25-0 |
| InChI | InChI=1/C18H18F3NO2/c1-2-3-11-24-17(23)15-9-4-5-10-16(15)22-14-8-6-7-13(12-14)18(19,20)21/h4-10,12,22H,2-3,11H2,1H3 |
Etofenamate EP Impurity B - Physico-chemical Properties
| Molecular Formula | C18H18F3NO2 |
| Molar Mass | 337.34 |
| Density | 1.2230 (estimate) |
| Boling Point | 170°C/1mmHg(lit.) |
| Flash Point | 192.2°C |
| Vapor Presure | 0Pa at 25℃ |
| Appearance | clear liquid |
| Color | White to Yellow to Green |
| Merck | 14,4132 |
| pKa | -2.36±0.50(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Refractive Index | 1.5530 to 1.5570 |
| Use | This product is for scientific research only and shall not be used for other purposes. |
Etofenamate EP Impurity B - Risk and Safety
| RTECS | DH8511000 |
Etofenamate EP Impurity B - Reference Information
| LogP | 6.92 |
| Introduction | the main component of Butyl Flufenamate Ointment is butyl flufenamate, which belongs to non-steroidal anti-inflammatory drugs and can be in the body's cells, arachidonic acid is blocked to produce inflammatory mediators such as prostaglandins and leukotrienes. And its characteristics, it is a strong anti-inflammatory activity, can have anti-inflammatory and anti-itching effect. Moreover, since it has an inhibitory effect on the hyperpermeability under the blood vessels of the skin, it also has an inhibitory effect on some acute inflammation and delayed allergic reactions. |
| pharmacological action | is a non-steroidal anti-inflammatory analgesic for external use. The mechanism of its anti-inflammatory and analgesic effects may be related to its membrane stabilization and inhibition of the production of some inflammatory mediators. |
| pharmacokinetics | at home and abroad, there is still a lack of detailed human pharmacokinetics research data. According to foreign reports, 14C-Butyl Flufenamate Ointment applied to the skin of rats after 72 hours, healthy skin percutaneous absorption of about 70%, slightly increased skin abrasion. Butyl flufenamate is up to 95% cumulative in relatively shallow skin and is present as a prototype. This product in the circulation of blood concentration is very low, and by hydrolysis and metabolism. |
| biological activity | Ufenamate (fluid acid butyl ester) is an anti-inflammatory drug based on anthranilic acid. Ufenamate can be used in the study of skin diseases such as acute and chronic eczema, contact dermatitis, diaper dermatitis, melasma and atopic dermatitis. |
| category | toxic substances |
| toxicity grade | poisoning |
| Acute toxicity | oral-rat LD50: 510 mg/kg; Oral-mouse LD50: 3100 mg/kg |
| flammability hazard characteristics | thermal decomposition of toxic nitrogen oxides, fluoride smoke |
| storage and transportation characteristics | warehouse ventilation and low temperature drying |
| fire extinguishing agent | water, dry powder, carbon dioxide, foam |
Last Update：2024-04-09 21:04:16
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Product Name: ufenamate Visit Supplier Webpage Request for quotationCAS: 67330-25-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Product Name: Ufenamate Request for quotation
CAS: 67330-25-0
Tel: 0086-571-88899366
Email: info@sxbxpharm.com
Mobile: 15167562001
QQ: 3538243465@qq.comSend QQ message
CAS: 67330-25-0
Tel: 0086-571-88899366
Email: info@sxbxpharm.com
Mobile: 15167562001
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